The NDUFA1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NDUFA1. This antibody recognizes Human antigen. The NDUFA1 Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane